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Bivatuzumab mertansine

Drug Profile

Bivatuzumab mertansine

Alternative Names: Anti-CD44v6-DM1 immunoconjugate; BIWI-1; Monoclonal antibody CD44v6-DM1 immunoconjugate

Latest Information Update: 31 Oct 2014

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At a glance

  • Originator Boehringer Ingelheim; ImmunoGen
  • Developer Boehringer Ingelheim
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Maytansinoids; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; CD44 antigen inhibitors; Mitosis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Breast cancer; Head and neck cancer

Most Recent Events

  • 14 Feb 2005 Discontinued - Phase-I for Head and neck cancer in Germany (IV)
  • 04 Dec 2001 Preclinical development for Cancer in Germany (Unknown route)
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