Ridaforolimus - Medinol

Drug Profile

Ridaforolimus - Medinol

Alternative Names: AP 23573; BioNIR; Deforolimus; EluNIR; EluNIR™ Ridaforolimus-Eluting Coronary Stent System; Jenzyl; MedJ-01; MK-8669; NirSupreme

Latest Information Update: 04 Nov 2018

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At a glance

  • Originator ARIAD Pharmaceuticals
  • Developer ARIAD Pharmaceuticals; Medinol; Merck & Co
  • Class Antineoplastics; Macrolides; Vascular disorder therapies
  • Mechanism of Action MTOR protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Sarcoma
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Coronary artery restenosis
  • Preregistration Submission Withdrawal Sarcoma
  • Discontinued Breast cancer; Cancer; Endometrial cancer; Neurodegenerative disorders; Non-small cell lung cancer; Ovarian cancer; Prostate cancer; Renal cell carcinoma; Solid tumours

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 19 Apr 2018 Merck terminates phase II trial in Breast cancer (combination therapy, late-stage disease, metastatic disease, second-line therapy) (NCT01605396)
  • 04 Feb 2018 Merck and Ariad terminates a phase II extension trial for Solid tumours (In infants, In adolescents, In children, In adults) in USA (NCT00836927)
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