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DE 098

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Drug Profile

DE 098

Alternative Names: Anti-APO-1 monoclonal antibody; ARG-098; DE-098

Latest Information Update: 08 Jul 2026

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At a glance

  • Originator Centocor
  • Developer Argenes; AYUMI Pharma
  • Class Antirheumatics; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; CD95 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Rheumatoid arthritis

Most Recent Events

  • 02 Jul 2026 AYUMI Pharma has been acquired by GNI Group
  • 28 Jul 2015 Discontinued - Phase-I/II for Rheumatoid arthritis in Europe (Intra-articular)
  • 28 Jul 2015 Discontinued - Phase-II for Rheumatoid arthritis in Japan (Intra-articular)

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