Research programme: serotonin/histamine antagonists - Evolutec

Drug Profile

Research programme: serotonin/histamine antagonists - Evolutec

Alternative Names: EV 598; rEV 598

Latest Information Update: 19 Mar 2008

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At a glance

  • Originator Evolutec
  • Class Antiemetics; Antineoplastics; Glycoproteins
  • Mechanism of Action Histamine release inhibitors; Serotonin receptor antagonists; Serotonin release inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Malignant carcinoid syndrome; Nausea and vomiting

Most Recent Events

  • 25 Oct 2006 Suspended - Preclinical for Emesis in United Kingdom (Parenteral)
  • 14 Mar 2006 EV 598 is available for licensing (
  • 05 Sep 2005 This compound is still in active development - (BIO-2005)
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