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Palovarotene - Clementia Pharmaceuticals

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Drug Profile

Palovarotene - Clementia Pharmaceuticals

Alternative Names: Clm-001; IPN-60120; R-667; RAR-gamma; RG-667; RO-3300074; Sohonos

Latest Information Update: 13 Feb 2024

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At a glance

  • Originator Roche
  • Developer Clementia Pharmaceuticals; Ipsen; Roche
  • Class Benzoic acids; Eye disorder therapies; Naphthalenes; Pyrazoles; Small molecules
  • Mechanism of Action Retinoic acid receptor gamma agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Fibrodysplasia ossificans progressiva
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Fibrodysplasia ossificans progressiva
  • Discontinued Bone disorders; Dry eyes; Emphysema

Most Recent Events

  • 08 Feb 2024 Launched for Fibrodysplasia ossificans progressiva (In adolescents, In children, In adults) in USA (PO), before February 2024
  • 28 Nov 2023 Registered for Fibrodysplasia ossificans progressiva (In adolescents, In children, In adults) in Australia (PO)
  • 26 Oct 2023 Ipsen announces intention to launch Palovarotene in USA
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