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Labetuzumab I-131

Drug Profile

Labetuzumab I-131

Alternative Names: Anti-CEA monoclonal antibody MN 14-I-131; CEA-Cide-I-131; hAFP-Y-90; Humanised anti-CEA monoclonal antibody MN 14-I-131; IMMU-111

Latest Information Update: 26 Aug 2015

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At a glance

  • Originator Immunomedics
  • Class Antineoplastics; Monoclonal antibodies; Radiopharmaceuticals; Radiosensitisers
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Suspended Colorectal cancer
  • Discontinued Liver cancer; Thyroid cancer

Most Recent Events

  • 03 Jun 2008 Efficacy and adverse events data from a phase II trial in colorectal liver metastases presented at the 44th Annual Meeting of the American Society of Clinical Oncology (ASCO-2008)
  • 04 Jun 2007 Interim results from a phase II clinical trial in patients with resected liver metastases from primary colorectal cancer added to the adverse events and Cancer therapeutic trials sections
  • 19 Jun 2006 Data presented at the 42nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2006) have been added to the Cancer therapeutic trials section
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