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Inotuzumab ozogamicin - Pfizer

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Drug Profile

Inotuzumab ozogamicin - Pfizer

Alternative Names: BESPONSA; CMC-544; InO - Pfizer; PF-05208773; PF-5208773; WAY-207294

Latest Information Update: 04 Feb 2025

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At a glance

  • Originator Celltech Group; Wyeth
  • Developer Pfizer
  • Class Antineoplastics; Cytostatic antibiotics; Drug conjugates; Immunotoxins; Monoclonal antibodies
  • Mechanism of Action DNA damage stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Precursor cell lymphoblastic leukaemia-lymphoma
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Precursor B-cell lymphoblastic leukaemia-lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma
  • Phase I/II Chronic myeloid leukaemia
  • Phase I Acute biphenotypic leukaemia; Burkitt's lymphoma
  • Discontinued Diffuse large B cell lymphoma; Non-Hodgkin's lymphoma

Most Recent Events

  • 07 Dec 2024 Efficacy and adverse events data from phase II EWALL-INO trial in Precursor B cell lymphoblastic leukaemia-lymphoma presented at the 66th American Society of Hematology Annual Meeting and Exposition (ASH-2024)
  • 07 Dec 2024 Efficacy data from a phase II trial in Precursor B-cell lymphoblastic leukaemia-lymphoma presented at the (full name of conference 66th American Society of Hematology Annual Meeting and Exposition (ASH-2024)
  • 26 Mar 2024 Launched for Precursor cell lymphoblastic leukaemia-lymphoma (In children, Second-line therapy or greater) in Japan (IV)

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