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Drug Profile


Alternative Names: CL 220075; DOV 220075

Latest Information Update: 02 Mar 2009

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At a glance

  • Originator Wyeth
  • Developer DOV Pharmaceutical; XTL Biopharmaceuticals
  • Class Heterocyclic bicyclo compounds; Non-opioid analgesics; Small molecules
  • Mechanism of Action Adrenergic receptor antagonists; Dopamine uptake inhibitors; Serotonin uptake inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Diabetic neuropathies; Osteoarthritis; Pain

Most Recent Events

  • 18 Nov 2008 Top-line efficacy data from a phase IIb trial in Diabetic neuropathic pain released by XTL Biopharmaceuticals
  • 09 Oct 2008 XTL Biopharmaceuticals completes a phase IIb trial in Diabetic neuropathies in US, Germany, Israel and India
  • 30 Jun 2008 XTL completes randomisation in its phase IIb trial for diabetic neuropathic pain in the US, Germany, Israel & India
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