X4P 001

Drug Profile

X4P 001

Alternative Names: AMD-070; AMD11070; X4P 001 RD; X4P-001-IO; X4P001

Latest Information Update: 18 Dec 2017

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At a glance

  • Originator AnorMED
  • Developer X4 Pharmaceuticals
  • Class Antineoplastics; Benzimidazoles; Diamines; Hydroquinones; Small molecules
  • Mechanism of Action CXCR4 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Immunodeficiency disorders
  • Phase II Renal cell carcinoma
  • Phase I/II Malignant melanoma
  • Phase I Solid tumours
  • Discontinued HIV-1 infections

Most Recent Events

  • 11 Dec 2017 Interim efficacy and adverse events data from a phase II/III trial Immunodeficiency disorders (WHIM Syndrome) presented at the 59th Annual Meeting of the American Society for Haematology (ASH-2017)
  • 16 Nov 2017 Phase-I/II clinical trials in Malignant melanoma (Combination therapy, Late-stage disease, Neoadjuvant therapy) in USA (PO) (NCT02823405)
  • 16 Nov 2017 Phase-I/II clinical trials in Malignant melanoma (Late-stage disease, Monotherapy, Neoadjuvant therapy) in USA (PO) (NCT02823405)
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