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Amitifadine

Drug Profile

Amitifadine

Alternative Names: Amitifadine hydrochloride; DOV-21947; EB-1010

Latest Information Update: 28 Oct 2021

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At a glance

  • Originator DOV Pharmaceutical
  • Developer Ethismos Research; Euthymics Bioscience
  • Class Antidepressants; Chlorobenzenes; Pyrrolidines; Small molecules
  • Mechanism of Action Adrenergic uptake inhibitors; Dopamine uptake inhibitors; Serotonin uptake inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Depressive disorders; Opioid-related disorders; Pain; Substance-related disorders
  • No development reported Alcoholism; Smoking withdrawal
  • Discontinued Major depressive disorder; Obesity

Most Recent Events

  • 28 Oct 2021 No recent reports of development identified for preclinical development in Alcoholism in USA (PO)
  • 28 Oct 2021 No recent reports of development identified for preclinical development in Smoking-withdrawal in USA (PO)
  • 23 Sep 2020 Ethismos Research plans a phase IIb trials for Smoking withdrawal in USA (PO) (Ethismos Research pipeline, September 2020)
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