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OPC 1

Drug Profile

OPC 1

Alternative Names: AST-OPC1; GRNOPC 1; hESC-derived oligodendrocyte progenitor cells (OPC) - Geron/University of California; Oligodendrocyte progenitor cells - Lineage Cell Therapeutics; OPC-1

Latest Information Update: 28 Oct 2019

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At a glance

  • Originator Geron Corporation
  • Developer Asterias Biotherapeutics; Lineage Cell Therapeutics
  • Class Stem cell therapies
  • Mechanism of Action Cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Spinal cord injuries
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Spinal cord injuries
  • No development reported Canavan disease; Multiple sclerosis; Stroke
  • Discontinued Alzheimer's disease

Most Recent Events

  • 12 Nov 2019 Lineage Cell Therapeutics announces to conduct a meeting with the US FDA to discuss the manufacturing and clinical development of OPC1 around the middle of 2020
  • 28 Oct 2019 No recent reports of development identified for preclinical development in Canavan disease in USA (Intralesional, Injection)
  • 28 Oct 2019 No recent reports of development identified for preclinical development in Multiple-sclerosis in USA (Intralesional, Injection)
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