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Lintuzumab Ac 225 - Actinium Pharmaceuticals

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Drug Profile

Lintuzumab Ac 225 - Actinium Pharmaceuticals

Alternative Names: 225Ac-HuM-195; 225Ac-lintuzumab; Ac-225-Lintuzumab; AC225 MOAB M195; Ac225 monoclonal antibody M195; Actimab-A; Actimab-M; Actimab-MDS; Actinium-225 (225Ac)-Lintuzumab; Actinium-225-labelled HuM195; HuM195-Ac-225

Latest Information Update: 26 Nov 2024

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At a glance

  • Originator PDL BioPharma
  • Developer Actinium Pharmaceuticals; Baylor Research Institute; Memorial Sloan-Kettering Cancer Center; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Drug conjugates; Immunoconjugates; Monoclonal antibodies; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity No

Highest Development Phases

  • Phase II Acute myeloid leukaemia
  • Preclinical Solid tumours
  • No development reported Multiple myeloma; Myelodysplastic syndromes

Most Recent Events

  • 18 Nov 2024 Actinium Pharmaceuticals plans a phase II/III trial for Lintuzumab Ac-225 for Acute myeloid leukemia (Combination therapy, Second-line therapy or greater)
  • 17 Jun 2024 Pharmacodynamics data from a preclinical trial in Acute myeloid leukaemia released by Actinium Pharmaceuticals
  • 11 Jun 2024 Adverse events, efficacy and pharmacokinetics data from a phase-I trial in Acute myeloid leukaemia released by Actinium Pharmaceuticals

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