Omadacycline - Paratek Pharmaceuticals
Alternative Names: Amadacycline; BAY 73-6944; BAY 73-7388; MK-2764; Neopentyl aminomethylminocycline; NUZYRA; PTK-0796; ZL 2401Latest Information Update: 20 Jun 2024
At a glance
- Originator Tufts University
- Developer Merck & Co; Paratek Pharmaceuticals; ZAI Lab
- Class Anti-infectives; Anti-inflammatories; Antibacterials; Small molecules; Tetracyclines
- Mechanism of Action Protein synthesis inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Community-acquired pneumonia; Skin and soft tissue infections
- Preregistration Anthrax
- Phase II Cystitis; Nontuberculous mycobacterium infections; Pyelonephritis; Urinary tract infections
- Phase I Bacterial infections
- No development reported Acute sinusitis; Plague
- Discontinued Nosocomial infections
Most Recent Events
- 16 Apr 2024 Zai Lab initiates a phase I trial (In volunteers) in China (PO) (NCT06462326)
- 27 Mar 2024 Paratek Pharmaceuticals completes phase IIIb trial for Community-acquired pneumonia in Bulgaria, Croatia, Georgia, Hungary, Poland, Russia, Serbia and Ukraine (IV, PO) (EudraCT2020-002986-32) (NCT04779242)
- 05 Mar 2024 Preclinical trials in Anthrax in USA (Inhalation) prior to March 2024