Recombinant alkaline phosphatase - AM-Pharma Holding

Drug Profile

Recombinant alkaline phosphatase - AM-Pharma Holding

Alternative Names: Human recombinant alkaline phosphatase; recAP; Recombinant optimised human alkaline phosphatase

Latest Information Update: 14 Mar 2018

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At a glance

  • Originator AM-Pharma Holding
  • Developer AM-Pharma
  • Class Phosphoric monoester hydrolases; Recombinant proteins
  • Mechanism of Action Endotoxin inhibitors; Enzyme replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hypophosphatasia
  • New Molecular Entity Yes
  • Available For Licensing Yes - Ulcerative colitis

Highest Development Phases

  • Phase II Acute kidney injury
  • Preclinical Hypophosphatasia
  • No development reported Ulcerative colitis
  • Discontinued Septic shock

Most Recent Events

  • 09 Mar 2018 Interim efficacy and adverse events data from the phase II STOP-AKI trial in Acute kidney injury released by AM-Pharma Holding
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Ulcerative-colitis in Netherlands (PO)
  • 22 May 2017 AM-Pharma completes enrolment in the STOP-AKI phase II trial for Acute kidney injury in Austria, Belgium, Czech Republic, Finland, France, Italy, Netherlands, Spain, United Kingdom and USA
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