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Research programme: JNK pathway inhibitors - Pharmascience

Drug Profile

Research programme: JNK pathway inhibitors - Pharmascience

Alternative Names: AEG 3482

Latest Information Update: 02 Jun 2011

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At a glance

  • Originator Aegera Therapeutics
  • Class Small molecules; Sulfonamides; Sulfones; Sulfoxides; Thiadiazoles
  • Mechanism of Action JNK mitogen-activated protein kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Discontinued Cancer; Diabetic neuropathies; Neuropathic pain; Peripheral nervous system diseases

Most Recent Events

  • 25 Mar 2008 A lead compound from this programme has entered clinical development
  • 16 Mar 2007 Aegera Therapeutics initiates an accelerated screening programme to identify replacement compound(s) for AEG 33783
  • 11 Apr 2006 Data presented at the 231st ACS National Meeting (231st-ACS-2006) have been added to the Neurological disorders pharmacodynamics section
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