Elesclomol - Synta Pharmaceuticals
Alternative Names: Elesclomol sodium; STA-4783Latest Information Update: 05 Nov 2023
At a glance
- Originator Synta Pharmaceuticals
- Developer Gynecologic Oncology Group; National Cancer Institute (USA); Synta Pharmaceuticals
- Class Antineoplastics; Hydrazines; Ketones; Small molecules; Thiones
- Mechanism of Action Apoptosis stimulants; Chelating agents; HSP70 heat shock protein stimulants; Reactive oxygen species stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Acute myeloid leukaemia; Cancer; Fallopian tube cancer; Malignant melanoma; Non-small cell lung cancer; Ovarian cancer; Peritoneal cancer; Prostate cancer; Sarcoma
Most Recent Events
- 15 Mar 2016 Synta Pharmaceuticals enter into an asset purchase agreement with a third party (Synta Pharmaceuticals, Form 10-K, March 2016)
- 13 Aug 2015 Elesclomol is still in phase II trials for Ovarian cancer (Combination therapy, Second-line therapy or greater) in the USA
- 09 Apr 2014 Discontinued - Phase-I for Prostate cancer (combination therapy, hormone refractory, late-stage disease, metastatic disease) in USA (IV)