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Lubiprostone - Mallinckrodt

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Drug Profile

Lubiprostone - Mallinckrodt

Alternative Names: Amitiza; LUBOWEL; RU-0211; SPI-0211; SPIRU-211

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Sucampo Pharmaceuticals
  • Developer Mallinckrodt plc; Sucampo Pharmaceuticals; Takeda
  • Class Gastrokinetics; Irritable bowel syndrome therapies; Laxatives; Monounsaturated fatty acids; Prostaglandins; Small molecules
  • Mechanism of Action Chloride channel agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Constipation; Irritable bowel syndrome
  • Discontinued Postoperative ileus

Most Recent Events

  • 01 Oct 2018 Yokohama City University completes the LUBIPRONE trial for constipation in Japan (PO, capsule) in March 2017 (UMIN000026635)
  • 30 Apr 2018 Launched for Constipation (In adolescents, In children) in USA (PO)
  • 30 Apr 2018 Registered for Constipation (In adolescents, In children) in USA (PO)

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