Drug Profile

Baricitinib - Eli Lilly and Company/Incyte Corporation

Alternative Names: INCB 028050; INCB 28050; LY 3009104; Olumiant

Latest Information Update: 20 Aug 2026

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At a glance

Originator Incyte Corporation
Developer Eli Lilly; Eli Lilly and Company; Incyte Corporation; Natco Pharma
Class Acetonitriles; Anti-inflammatories; Antipsoriatics; Antirheumatics; Azetidines; Eye disorder therapies; Pyrazoles; Pyrimidines; Pyrroles; Skin disorder therapies; Small molecules
Mechanism of Action Janus kinase 1 inhibitors; Janus kinase 2 inhibitors; TYK2 kinase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

Yes - Systemic lupus erythematosus
New Molecular Entity Yes

Marketed Alopecia areata; Atopic dermatitis; Rheumatoid arthritis
Registered COVID 2019 infections
Phase III Diabetes mellitus; Juvenile rheumatoid arthritis; Type 1 diabetes mellitus; Uveitis
Phase II/III Aicardi-Goutieres syndrome; Hereditary autoinflammatory diseases
Discontinued Diabetic nephropathies; Primary biliary cirrhosis; Psoriasis; Psoriatic arthritis; Systemic lupus erythematosus

22 May 2026 Eli Lilly and Company completes phase-III clinical trials in Atopic dermatitis (In adolescents, In children) in Argentina, Germany, Poland, Spain and United Kingdom, Australia, Austria, Brazil, Czech Republic, France, Hungary, India, Israel, Japan, Mexico, Russia, Taiwan (PO) (NCT03952559) (EudraCT2018-000349-38)
31 Mar 2026 Updated efficacy data from the phase-II/III BRAVE-AA1 trial in Alopecia areata presented at theAmerican Academy of Dermatology annual Meeting-2026 (AAD-2026)
27 Feb 2026 Preregistration for Alopecia areata (In adolescents) in European Union (PO)

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