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Baricitinib - Eli Lilly and Company/Incyte Corporation

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Drug Profile

Baricitinib - Eli Lilly and Company/Incyte Corporation

Alternative Names: INCB 028050; INCB 28050; LY 3009104; Olumiant

Latest Information Update: 02 Feb 2024

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At a glance

  • Originator Incyte Corporation
  • Developer Eli Lilly; Eli Lilly and Company; Incyte Corporation; Natco Pharma
  • Class Acetonitriles; Anti-inflammatories; Antipsoriatics; Antirheumatics; Azetidines; Eye disorder therapies; Pyrazoles; Pyrimidines; Pyrroles; Skin disorder therapies; Small molecules
  • Mechanism of Action Janus kinase 1 inhibitors; Janus kinase-2 inhibitors; TYK2 kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Systemic lupus erythematosus
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Alopecia areata; Atopic dermatitis; Rheumatoid arthritis
  • Registered COVID 2019 infections
  • Phase III Juvenile rheumatoid arthritis; Uveitis
  • Phase II/III Aicardi-Goutieres syndrome; Hereditary autoinflammatory diseases
  • Phase II Giant cell arteritis; Myositis; Polymyalgia rheumatica; Primary biliary cirrhosis; Systemic lupus erythematosus
  • Discontinued Diabetic nephropathies; Psoriasis; Psoriatic arthritis

Most Recent Events

  • 30 Jan 2024 Registered for Alopecia areata in Canada (PO)
  • 25 Sep 2023 University of Manchester in collaboration with Eli Lilly and Company completes phase-II MYOJAK trial in Myositis in United Kingdom (PO) (EudraCT2019-003868-42) (NCT04208464)
  • 30 Aug 2023 Eli Lilly and Company completes a phase II trial in Polymyalgia rheumatica in France (PO, Tablet) (NCT04027101)
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