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Baricitinib - Eli Lilly/Incyte Corporation

Drug Profile

Baricitinib - Eli Lilly/Incyte Corporation

Alternative Names: INCB-028050; INCB-28050; LY-3009104; Olumiant

Latest Information Update: 06 Feb 2019

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At a glance

  • Originator Incyte Corporation
  • Developer Eli Lilly; Incyte Corporation
  • Class Acetonitriles; Antipsoriatics; Antirheumatics; Azetidines; Pyrazoles; Pyrimidines; Pyrroles; Skin disorder therapies; Small molecules; Uroprotectives
  • Mechanism of Action Janus kinase 1 inhibitors; Janus kinase-2 inhibitors; TYK2 kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Rheumatoid arthritis
  • Phase III Atopic dermatitis; Juvenile rheumatoid arthritis; Systemic lupus erythematosus
  • Phase II/III Alopecia areata
  • Phase II Giant cell arteritis
  • Clinical Phase Unknown Psoriatic arthritis
  • Preclinical Primary biliary cirrhosis
  • Discontinued Diabetic nephropathies; Psoriasis

Most Recent Events

  • 05 Feb 2019 Topline adverse events data from the phase-III BREEZE-AD1 and BREEZE-AD2 trial in Atopic dermatitis released by Eli Lilly
  • 17 Dec 2018 Phase-III clinical trials in Juvenile rheumatoid arthritis (In children, In adolescents, Treatment-experienced) in Japan (PO) (NCT03773978)
  • 17 Dec 2018 Eli Lilly and Company plans the JUVE-BASIS phase III trial for Juvenile Idiopathic Arthritis in Brazil, Germany, Japan, Mexico and Russia , (NCT03773978)
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