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Gabapentin enacarbil - Arbor Pharmaceuticals

Drug Profile

Gabapentin enacarbil - Arbor Pharmaceuticals

Alternative Names: 1838262; ASP8825; Gabapentin-XP; GSK 1838262; Horizant; Regnite; Solzira; XP13512

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator XenoPort
  • Developer Arbor Pharmaceuticals; Astellas Pharma; GlaxoSmithKline; National Institute on Alcohol Abuse and Alcoholism; XenoPort
  • Class Acetic acids; Antiepileptic drugs; Carbamates; Cyclohexanecarboxylic acids; Gabapentinoids; Small molecules
  • Mechanism of Action CACNA2D1 protein modulators; GABA receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Restless legs syndrome

Highest Development Phases

  • Marketed Postherpetic neuralgia; Restless legs syndrome
  • Discontinued Alcoholism; Diabetic neuropathies; Migraine

Most Recent Events

  • 01 Sep 2021 Gabapentin enacarbil contains boxed warning of somnolence/sedation and dizziness
  • 05 Apr 2021 Discontinued - Phase-II for Alcoholism in USA (PO)
  • 11 Mar 2019 No development reported - Phase-II for Alcoholism in USA (PO)
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