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Pegadricase - 3SBio/Cartesian Therapeutics

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Drug Profile

Pegadricase - 3SBio/Cartesian Therapeutics

Alternative Names: Pegsitacase; Pegsiticase; PEGylated recombinant candida urate oxidase; SEL 037; SSS11; Uricase-PEG 20

Latest Information Update: 11 Oct 2024

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At a glance

  • Originator Phoenix Pharmacologics
  • Developer 3SBio; Cartesian Therapeutics
  • Class Enzymes; Oxidoreductases; Polyethylene glycols; Recombinant proteins
  • Mechanism of Action Urate oxidase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Tumour lysis syndrome; Gout; Lesch-Nyhan syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Gout
  • Phase I/II Tumour lysis syndrome
  • Phase I Hyperuricaemia

Most Recent Events

  • 28 Nov 2022 No recent reports of development identified for phase-I development in Gout(In volunteers) in China (IV, Injection)
  • 28 Nov 2020 No recent reports of development identified for phase-I development in Gout(In volunteers) in China (IV, Infusion)
  • 09 Aug 2019 Shenyang Sunshine Pharmaceutical plans a phase I pharmacokinetic trial in Chinese healthy volunteers in China in August 2019 (NCT04047394)

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