Plozalizumab

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Drug Profile

Plozalizumab

Alternative Names: Anti-CCR2 monoclonal antibody; MLN-1202; TAK-202

Latest Information Update: 24 Mar 2018

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At a glance

  • Originator Millennium Pharmaceuticals
  • Developer Millennium; Millennium Pharmaceuticals; Takeda; Takeda Oncology
  • Class Anti-inflammatories; Antineoplastics; Antirheumatics; Monoclonal antibodies
  • Mechanism of Action CCR2 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Atherosclerosis; Diabetic nephropathies
  • Phase I Malignant melanoma; Solid tumours
  • Discontinued Multiple sclerosis; Rheumatoid arthritis; Scleroderma

Most Recent Events

  • 28 Jul 2017 Phase-I clinical trials in Solid tumours in USA (Parenteral) (3285061; Takeda Q2 report,
  • 15 Dec 2016 Biomarkers information updated
  • 01 Oct 2016 Takeda withdraws a phase I trial in Healthy volunteers prior to enrollment in Japan due to a business decision and no safety or efficacy concerns (NCT02426021)
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