Allogeneic stem cell therapy - Athersys

Drug Profile

Allogeneic stem cell therapy - Athersys

Alternative Names: AMI MultiStem; HLCM 051; MultiStem; PF-05285401; PF-5285401

Latest Information Update: 14 Nov 2018

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At a glance

  • Originator Athersys
  • Developer Athersys; Case Western Reserve University; Healios; University of Texas Health Science Center at Houston
  • Class Anti-inflammatories; Antiparkinsonians; Cardiovascular therapies; Heart failure therapies; Stem cell therapies
  • Mechanism of Action Cell replacements; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Graft-versus-host disease
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Stroke
  • Phase II Graft-versus-host disease; Myocardial infarction
  • Phase I/II Respiratory distress syndrome
  • Phase I Transplant rejection
  • Preclinical Brain injuries; Heart failure; Multiple sclerosis; Peripheral arterial disorders; Spinal cord injuries
  • Discontinued Diabetes mellitus; Mucopolysaccharidosis I; Parkinson's disease; Ulcerative colitis

Most Recent Events

  • 06 Nov 2018 Healios’ option and negotiation period for further expansion of the collaboration with Athersys extended to 6 December 2018
  • 31 Jul 2018 Phase-III clinical trials in Stroke in USA (IV) (NCT03545607)
  • 24 Jun 2018 Biomarkers information updated
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