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HuMax IL8 - Bristol-Myers Squibb/Genmab

Drug Profile

HuMax IL8 - Bristol-Myers Squibb/Genmab

Alternative Names: anti-IL8 mAb - Bristol-Myers Squibb/Genmab; BMS-986253; HuMax-IL8; HuMax-Inflam; HuMax®-IL8; MDX 018

Latest Information Update: 18 Nov 2019

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At a glance

  • Originator Genmab; Medarex
  • Developer Bristol-Myers Squibb; Columbia University; Genmab; Icahn School of Medicine at Mount Sinai; Medarex
  • Class Anti-inflammatories; Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Interleukin 8 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Liver cancer; Non-small cell lung cancer
  • Phase I/II Prostate cancer; Solid tumours
  • Discontinued Autoimmune disorders; Glioblastoma; Palmoplantar pustulosis

Most Recent Events

  • 13 Nov 2019 Phase-II clinical trials in Liver cancer (Combination therapy, Neoadjuvant therapy) in USA (Parenteral) (NCT04123379)
  • 13 Nov 2019 Phase-II clinical trials in Non-small cell lung cancer (Combination therapy, Neoadjuvant therapy) in USA (Parenteral) (NCT04123379)
  • 15 Oct 2019 Icahn School of Medicine at Mount Sinai and Bristol-Myers Squibb plans a phase II trial for Non-small cell lung cancer and Hepatocellular carcinoma (Neoadjuvant therapy, In adults, In the elderly) in USA in November 2019 (Parenteral) (NCT04123379)
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