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Tecovirimat - SIGA Technologies

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Drug Profile

Tecovirimat - SIGA Technologies

Alternative Names: Arestvyr; SIGA-246; ST-246 Form I (monohydrate); ST-246 Form V (hemihydrate); ST-246®; Tecovirimat - SIGA Technologies; Tecovirimat monohydrate - SIGA Technologies; TPOXX

Latest Information Update: 21 Aug 2024

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At a glance

  • Originator ViroPharma
  • Developer National Institute of Allergy and Infectious Diseases; SIGA Technologies
  • Class Antivirals; Benzamides; Cyclopropanes; Fluorinated hydrocarbons; Isoindoles; Organic bridged compounds; Small molecules
  • Mechanism of Action Orthopoxvirus p37 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Smallpox; Orthopoxvirus infections
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Smallpox
  • Registered Monkeypox; Orthopoxvirus infections; Vaccinia

Most Recent Events

  • 15 Aug 2024 Efficacy and adverse events data from a phase II trial in Monkeypox released by SIGA Technologies
  • 11 Apr 2024 Preregistration for Monkeypox (In the elderly, In adults) in Japan (PO)
  • 11 Apr 2024 Preregistration for Smallpox in Japan (PO)

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