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CHS 131

Drug Profile

CHS 131

Alternative Names: AMG 131; INT 131; INT131 besylate; T 0903131; T 131

Latest Information Update: 17 Nov 2018

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At a glance

  • Originator Tularik
  • Developer Coherus BioSciences; InteKrin Therapeutics
  • Class Anti-inflammatories; Antihypercalcaemics; Antihyperglycaemics; Hepatoprotectants; Insulin sensitisers; Neuroprotectants; Small molecules
  • Mechanism of Action Peroxisome proliferator-activated receptor gamma agonists; Peroxisome proliferator-activated receptor gamma modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Multiple sclerosis; Type 2 diabetes mellitus
  • Preclinical Non-alcoholic steatohepatitis

Most Recent Events

  • 08 Nov 2018 Coherus Biosciences plans a phase II trial for Non-alcoholic steatohepatitis
  • 17 Aug 2018 Preclinical trials in Non-alcoholic steatohepatitis in USA (PO), prior to August 2018
  • 24 Jun 2018 Biomarkers information updated
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