Tapinarof - Celestial Pharmaceuticals/Stiefel Laboratories/Welichem Biotech

Drug Profile

Tapinarof - Celestial Pharmaceuticals/Stiefel Laboratories/Welichem Biotech

Alternative Names: Benvitimod; DHPS; GSK-2894512; WBI-1001

Latest Information Update: 23 Jul 2018

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At a glance

  • Originator Welichem Biotech
  • Developer Beijing Wenfeng Tianji Pharmaceuticals; Celestial Pharmaceuticals; Stiefel Laboratories; Welichem Biotech
  • Class Antipsoriatics; Nonsteroidal anti-inflammatories; Resorcinols; Skin disorder therapies; Small molecules; Stilbenes
  • Mechanism of Action Aryl hydrocarbon receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Psoriasis
  • Phase II Atopic dermatitis; Plaque psoriasis
  • No development reported Inflammatory bowel diseases

Most Recent Events

  • 12 Jul 2018 Dermavant Sciences signs agreement with GSK to purchase rights to tapinarof
  • 06 Dec 2017 GlaxoSmithKline withdraws a phase III trial prior to enrolment due to a business decision for Plaque psoriasis (Topical, Cream) (NCT03202004)
  • 29 Nov 2017 GlaxoSmithKline withdraws a phase I trial for Psoriasis (In volunteers) prior to enrolment, before November 2017 (NCT03201978)
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