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CCX 140

Drug Profile

CCX 140

Alternative Names: CCX-140B; CCX140

Latest Information Update: 16 Nov 2018

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At a glance

  • Originator ChemoCentryx
  • Developer ChemoCentryx; Vifor
  • Class Antihyperglycaemics; Small molecules
  • Mechanism of Action CCR2 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Focal segmental glomerulosclerosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Diabetic nephropathies; Focal segmental glomerulosclerosis
  • Research Kidney disorders
  • No development reported Type 2 diabetes mellitus
  • Discontinued Multiple sclerosis; Vascular restenosis

Most Recent Events

  • 10 Oct 2018 Chemical structure information added
  • 01 Oct 2018 ChemoCentryx initiates enrolment in the phase II LUMINA 2 trial for Focal Segmental Glomerulosclerosis in USA (NCT03703908)
  • 12 Sep 2018 CCX 140 receives Orphan Drug status for Focal segmental glomerulosclerosis in USA
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