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Amitriptyline/ketamine - Immune Pharmaceuticals

Drug Profile

Amitriptyline/ketamine - Immune Pharmaceuticals

Alternative Names: AmiKet; Amiket™ Nano; EpiCept™ NP-1; Ketamine/amitriptyline; NP-1

Latest Information Update: 09 Aug 2017

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At a glance

  • Originator EpiCept Corporation
  • Developer Immune Pharmaceuticals Inc; National Cancer Institute (USA)
  • Class Cyclohexanes; Dibenzocycloheptenes; Non-opioid analgesics; Small molecules; Tricyclic antidepressants
  • Mechanism of Action Adrenergic uptake inhibitors; Alpha 1 adrenergic receptor antagonists; NMDA receptor antagonists; Serotonin uptake inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Postherpetic neuralgia
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Diabetic neuropathies; Neuropathic pain; Postherpetic neuralgia

Most Recent Events

  • 07 Aug 2017 Amitriptyline/ketamine remains available for licensing as of 07 August 2017 (http://immunepharmaceuticals.com)
  • 16 Sep 2016 Immune Pharmaceuticals enters into a Binding agreement with Novel Pain Therapeutics to fund Maxim Pharmaceuticals
  • 18 Jul 2016 Immune Pharmaceuticals amends its option agreement with Novel Pain Therapeutics for Peripheral neuropathic pain
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