XL 784

Drug Profile

XL 784

Alternative Names: XL784

Latest Information Update: 17 Mar 2008

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At a glance

  • Originator Exelixis
  • Class Antineoplastics; Small molecules
  • Mechanism of Action ADAM10 protein inhibitors; Angiogenesis inhibitors; Matrix metalloproteinase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No

Highest Development Phases

  • Discontinued Cancer; Diabetic nephropathies

Most Recent Events

  • 18 Jan 2008 GlaxoSmithKline decides not to exercise its option to license XL 784
  • 07 Nov 2007 Final results from a Phase-II clinical trial in patients with Diabetic nephropathies added to the adverse events and Diabetes therapeutic trials sections
  • 16 Oct 2007 Exelixis completes a Phase-II trial in Diabetic nephropathies in USA
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