Sitagliptin - Merck & Co

Drug Profile

Sitagliptin - Merck & Co

Alternative Names: Glactiv; Januvia; MK-0431; MK-431; ONO-5435; Tesavel; Xelevia

Latest Information Update: 08 Aug 2018

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At a glance

  • Originator Merck & Co; Merck Sharp & Dohme
  • Developer Banyu; Merck & Co; Merck Sharp & Dohme; Ono Pharmaceutical; Pfizer; University of Colorado at Denver; Washington University School of Medicine
  • Class Antihyperglycaemics; Pyrazines; Small molecules; Triazoles
  • Mechanism of Action CD26 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Type 2 diabetes mellitus
  • Discontinued Type 1 diabetes mellitus

Most Recent Events

  • 23 Jun 2018 Efficacy and adverse events data from the phase III CompoSIT-I trial in Type 2 diabetes mellitus released by Merck
  • 23 Jun 2018 Efficacy and adverse events data from the phase III CompoSIT-R trial in Type 2 diabetes mellitus released by Merck
  • 22 Jun 2018 Efficacy and adverse events data from the phase III CompoSIT-R trial in Type 2 diabetes mellitus and Renal impairment presented at the (78th Annual Scientific Sessions of the American Diabetes Association) (ADA-2018)
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