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Solid tumour vaccine - Northwest Biotherapeutics

Drug Profile

Solid tumour vaccine - Northwest Biotherapeutics

Alternative Names: DCVax®-Direct; DCVax®-Direct adjuvant cancer therapy; DCVax®-Head & Neck; DCVax®-Liver; DCVax®-Lung; DCVax®-Pancreas

Latest Information Update: 20 Dec 2018

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At a glance

  • Originator Northwest Biotherapeutics
  • Developer Johannes Gutenberg-University Mainz; Northwest Biotherapeutics
  • Class Cancer vaccines; Dendritic cell vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Colorectal cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 14 Dec 2018 Northwest Biotherapeutics plans a phase II trial
  • 20 Aug 2018 Northwest Biotherapeutics and Mayo Clinic plans a phase Ib trial for Brain metastases from non-small cell lung cancer or breast cancer (Inoperable/Unresectable) in USA (Intratumoural) (NCT03638765)
  • 21 Sep 2016 Efficacy data from a phase I trial in Solid tumours released by Northwest Biotherapeutics
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