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SG 2000

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Drug Profile

SG 2000

Alternative Names: BN-2629; NCI 694501; NSC 694501; Project P011; SJG-136; SP 2001; UP-2001

Latest Information Update: 01 Aug 2019

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At a glance

  • Originator Spirogen
  • Developer National Cancer Institute (USA); Spirogen
  • Class Benzodiazepines; Cytostatic antibiotics; Pyrroles
  • Mechanism of Action DNA cross linking agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Acute myeloid leukaemia; Chronic lymphocytic leukaemia; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer

Most Recent Events

  • 01 Aug 2019 Discontinued - Phase-I/II for Acute myeloid leukaemia (Late-stage disease, Second-line therapy or greater) in USA (IV) (Spirogen pipeline, August 2019) (NCT02034227)
  • 01 Aug 2019 Discontinued - Phase-I/II for Chronic lymphocytic leukaemia (Late-stage disease, Second-line therapy or greater) in USA (IV) (Spirogen pipeline, August 2019) (NCT02034227)
  • 03 Dec 2015 Spirogen terminates a phase I/II trial for Chronic lymphocytic leukaemia and Acute myeloid leukaemia (Second-line therapy or greater, Late stage disease) in USA (NCT02034227)

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