Research programme: antibacterials - Replidyne

Drug Profile

Research programme: antibacterials - Replidyne

Alternative Names: Bacterial DNA polymerase inhibitors - Replidyne; Bacterial DNA primase inhibitors - Replidyne; REP 6021; tRNA synthetase inhibitors - Replidyne

Latest Information Update: 02 Mar 2009

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At a glance

  • Originator GlaxoSmithKline
  • Developer Cardiovascular Systems
  • Class Guanidines; Pyrimidinones
  • Mechanism of Action DNA synthesis inhibitors; Enzyme inhibitors; Protein synthesis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Suspended Bacterial infections; Methicillin-resistant Staphylococcus aureus infections

Most Recent Events

  • 27 Aug 2008 Suspended - Preclinical for Bacterial infections in USA (unspecified route)
  • 27 Aug 2008 Suspended - Preclinical for Meticillin-resistant Staphylococcus aureus infections in USA (Topical)
  • 12 Apr 2006 Data presented at the 231st American Chemical Society National Meeting (231st-ACS-2006) have been added to the Bacterial Infections antimicrobial activity section ,
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