Research programme: antibacterials - Replidyne
Alternative Names: Bacterial DNA polymerase inhibitors - Replidyne; Bacterial DNA primase inhibitors - Replidyne; REP 6021; tRNA synthetase inhibitors - ReplidyneLatest Information Update: 02 Mar 2009
At a glance
- Originator GlaxoSmithKline
- Developer Cardiovascular Systems
- Class Guanidines; Pyrimidinones
- Mechanism of Action DNA synthesis inhibitors; Enzyme inhibitors; Protein synthesis inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
Highest Development Phases
- Suspended Bacterial infections; Methicillin-resistant Staphylococcus aureus infections
Most Recent Events
- 27 Aug 2008 Suspended - Preclinical for Bacterial infections in USA (unspecified route)
- 27 Aug 2008 Suspended - Preclinical for Meticillin-resistant Staphylococcus aureus infections in USA (Topical)
- 12 Apr 2006 Data presented at the 231st American Chemical Society National Meeting (231st-ACS-2006) have been added to the Bacterial Infections antimicrobial activity section ,