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EDI 200

Drug Profile

EDI 200

Alternative Names: APO-200; EDI200; Fc EDA1; Fc:EDA-A1 fusion protein; Human immunoglobulin G1 constant region - human ectodysplasin-A1 receptor-binding domain fusion protein; Hypohidrotic ectodermal dysplasia therapy - Edimer; Recombinant ectodysplasin A1; Recombinant EDA1; XLHED therapy - Edimer

Latest Information Update: 23 Jan 2018

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At a glance

  • Originator Apoxis
  • Developer Edimer Pharmaceuticals
  • Class Immunoglobulin Fc fragments; Immunoglobulin fusion proteins; Recombinant fusion proteins; Tumour necrosis factors
  • Mechanism of Action Tumour necrosis factor receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Ectodermal dysplasia
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Ectodermal dysplasia

Most Recent Events

  • 01 Dec 2015 Edimer Pharmaceuticals completes a phase II trial for Ectodermal dysplasia (in neonates, treatment-naive) in USA, United Kingdom, France, Germany, and Italy (NCT01775462)
  • 01 Aug 2014 TopoTarget has merged with BioAlliance Pharma to form Onxeo SA
  • 24 Jun 2014 Edimer Pharmaceuticals enters into collaboration with InformedDNA for the development of EDI 200
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