AME 527

Drug Profile

AME 527

Latest Information Update: 26 Mar 2009

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At a glance

  • Originator Applied Molecular Evolution
  • Class Antirheumatics; Monoclonal antibodies
  • Mechanism of Action Tumour necrosis factor alpha inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Rheumatoid arthritis

Most Recent Events

  • 24 Nov 2005 Phase-I/II clinical trials in Rheumatoid arthritis in USA (unspecified route)
  • 24 Nov 2005 Data presented at the 69th Annual Scientific Meeting of the American College of Rheumatology and the 40th Annual Meeting of the Association of Rheumatology Health Professionals (ACR/ARHP-2005) have been added to the adverse events and Rheumatic disease pharmacodynamics sections
  • 16 Feb 2004 Applied Molecular Evolution has been acquired by Eli Lilly
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