Chlorproguanil/dapsone/artesunate

Drug Profile

Chlorproguanil/dapsone/artesunate

Alternative Names: CDA; Dacart; LAPDAP + artesunate

Latest Information Update: 20 Oct 2016

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At a glance

  • Originator GlaxoSmithKline
  • Developer GlaxoSmithKline; Medicines for Malaria Venture; Special Programme for Research and Training in Tropical Diseases
  • Class Antimalarials; Artemisinins; Biguanides; Sesquiterpenes; Sulfones
  • Mechanism of Action Antimetabolites; Tetrahydrofolate dehydrogenase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Malaria

Most Recent Events

  • 08 Feb 2008 Chlorproguanil/dapsone/artesunate is still in phase III trials for uncomplicated malaria in sub-Saharan Africa
  • 26 Jul 2006 GlaxoSmithKline and Medicines for Malaria Venture have initiated two phase III trials for malaria in sub-Saharan Africa
  • 30 Nov 2005 Phase-III clinical trials in Malaria treatment in Africa (PO, Tablet)
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