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Research programme: kinase inhibitors - Daiichi Sankyo/Teva Pharmaceutical Industries

Drug Profile

Research programme: kinase inhibitors - Daiichi Sankyo/Teva Pharmaceutical Industries

Alternative Names: CEP-17940; CEP-18050; CEP-28122; CEP-31933; CEP-40783; CEP-4416; CEP-7055; CEP-A; RXDX-106

Latest Information Update: 26 Jun 2018

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At a glance

  • Originator Ambit Biosciences Corporation; Cephalon
  • Developer Daiichi Sankyo Company; Ignyta; Teva Pharmaceutical Industries
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Anaplastic lymphoma kinase inhibitors; Axl receptor tyrosine kinase inhibitors; Proto oncogene protein b raf inhibitors; Proto oncogene protein c met inhibitors; Proto-oncogene protein c-mer inhibitors; TYRO3 receptor protein tyrosine kinase antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Non-Hodgkin's lymphoma; Solid tumours

Most Recent Events

  • 29 Dec 2017 US FDA approves IND application for RXDX 106 in Solid tumours (Late-stage disease, Metastatic disease)
  • 10 Nov 2017 Preclinical development is ongoing in USA
  • 08 Nov 2017 Ignyta plans the phase I TITAN trial of RXDX 106 for Solid tumours (Late-stage disease; Metastatic disease; Second-line treatment or greater) (NCT03454243)
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