Azacitidine - Pfizer

Drug Profile

Azacitidine - Pfizer

Alternative Names: 5-azacytidine; Aza-C; Azacytidine; CC-486; Ladakamycin; NS-17; NSC-102816; U-18496; Vidaza

Latest Information Update: 28 Feb 2018

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At a glance

  • Originator Pharmacia Corporation
  • Developer Australasian Leukaemia & Lymphoma Group; Celgene Corporation; H. Lee Moffitt Cancer Center and Research Institute; Karolinska University Hospital; Nippon Shinyaku; Pfizer; University Hospital Regensburg; University of Colorado at Denver; University of Kansas Medical Center; University of Texas M. D. Anderson Cancer Center; University of Utah; Washington University School of Medicine; Weill Cornell Medical College
  • Class Antineoplastics; Aza compounds; Pyrimidine nucleosides; Ribonucleosides; Small molecules
  • Mechanism of Action Antimetabolites; DNA methylation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Myelodysplastic syndromes; Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Acute myeloid leukaemia; Chronic myelomonocytic leukaemia; Myelodysplastic syndromes
  • Phase II Breast cancer; Leukaemia; Nasopharyngeal cancer; Non-small cell lung cancer
  • Phase I/II Colorectal cancer; Diffuse large B cell lymphoma; Renal cancer; Solid tumours
  • No development reported Lymphoma; Multiple myeloma

Most Recent Events

  • 28 Feb 2018 No recent reports of development identified for phase-I development in Lymphoma(Combination therapy, First-line therapy, Late-stage disease) in USA (PO)
  • 31 Jan 2018 Launched for Acute myeloid leukaemia (In the elderly, Newly diagnosed) in China (SC)
  • 31 Jan 2018 Launched for Myelodysplastic syndromes in China (SC)
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