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Research programme: p53 upregulated modulator of apoptosis stimulants - Merck & Co

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Drug Profile

Research programme: p53 upregulated modulator of apoptosis stimulants - Merck & Co

Alternative Names: ARQ-850RP; Research programme: PUMA stimulants - ArQule

Latest Information Update: 20 Jan 2020

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At a glance

  • Originator ArQule
  • Developer Merck & Co
  • Class Small molecules
  • Mechanism of Action Apoptosis stimulants; Tumour suppressor protein p53 stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Solid tumours

Most Recent Events

  • 16 Jan 2020 ArQule has been acquired and merged into Merck & Co
  • 31 May 2006 This programme is still in active development
  • 31 Aug 2005 Preclinical trials in Solid tumours in USA (unspecified route)

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