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Research programme: short interfering RNA-based therapeutics - Silence Therapeutics

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Drug Profile

Research programme: short interfering RNA-based therapeutics - Silence Therapeutics

Alternative Names: GalNAc-siRNA - Silence Therapeutics; ICS-283; Research programme: RNAi-based therapeutics -Intradigm/Qiagen

Latest Information Update: 02 Oct 2021

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At a glance

  • Originator Intradigm Corporation
  • Developer Intradigm Corporation; OPKO Health; Silence Therapeutics
  • Class Amino sugars; Cardiovascular therapies; Drug conjugates; Small interfering RNA
  • Mechanism of Action RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Acromegaly; Alcoholism; Metabolic disorders
  • Discontinued Age-related macular degeneration; Cancer; Coronavirus infections; Diabetic retinopathy

Most Recent Events

  • 28 Apr 2021 No recent reports of development identified for research development in Acromegaly in United Kingdom (Parenteral)
  • 28 Apr 2021 No recent reports of development identified for research development in Alcoholism in United Kingdom (Parenteral)
  • 28 Nov 2020 No recent reports of development identified for research development in Metabolic-disorders in United Kingdom (Parenteral)

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