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Orticumab - Abcentra

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Drug Profile

Orticumab - Abcentra

Alternative Names: 2D03; Anti-oxLDL; BI-204; MLDL-1278A; RG-7418

Latest Information Update: 21 Apr 2025

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At a glance

  • Originator BioInvent International
  • Developer Abcentra; BioInvent International; Genentech
  • Class Anti-inflammatories; Antibodies; Antihyperlipidaemics; Antipsoriatics; Cardiovascular therapies; Monoclonal antibodies
  • Mechanism of Action Immunomodulators; LDL receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Psoriasis
  • No development reported Aortic valve stenosis; Atherosclerosis

Most Recent Events

  • 17 Apr 2025 Abcentra plans the phase II FORTIFY trial for Coronary artery disease and Inflammation (Parenteral), in June 2025 (NCT06927739)
  • 06 Apr 2024 Efficacy data from phase II trial in Psoriasis presented at 73rd Annual Scientific Session of the American College of Cardiology (ACC-2024)
  • 28 Jul 2023 No recent reports of development identified for preclinical development in Aortic-valve-stenosis in USA (Parenteral)

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