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CV 301

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Drug Profile

CV 301

Alternative Names: CEA-MUC-1-TRICOM Vaccine; CEA-MUC-1/TRICOM; CV-301; CVAC-301; Falimarev-inalimarev; Inalimarev-falimarev; PANVAC; PANVAC V/F; PANVAC-VF

Latest Information Update: 23 Oct 2023

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At a glance

  • Originator Therion Biologics
  • Developer BN ImmunoTherapeutics; Bristol-Myers Squibb; National Cancer Institute (USA); Therion Biologics
  • Class Cancer vaccines; Membrane glycoproteins
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Pancreatic cancer
  • Phase II Bladder cancer; Colorectal cancer; Non-small cell lung cancer; Prostate cancer
  • Discontinued Breast cancer; Ovarian cancer

Most Recent Events

  • 01 Aug 2023 Georgetown University terminates a phase I/II trial in Pancreatic cancer and Colorectal cancer (Combination therapy, Metastatic disease, Second-line therapy or greater) in USA (SC), due to lack of enrollment (NCT03376659)
  • 10 Sep 2021 Efficacy data from a phase II trial in Bladder cancer presented at the 116th Annual Meeting of the American Urological Association (AUA-2021)
  • 19 Feb 2021 Phase II development in Prostate cancer (Combination therapy, Metastatic disease) is still ongoing in USA (SC) (NCT03315871)

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