Research programme: natural killer cell cancer therapies - NantKwest

Drug Profile

Research programme: natural killer cell cancer therapies - NantKwest

Alternative Names: CD19 target activated natural killer cellular therapy - NantKwest; CD19.t-haNK; CD19.t-haNK therapy - NantKwest; CD19.taNK therapy - NantKwest; CS1 target activated natural killer cellular therapy- NantKwest; CS1.taNK therapy - NantKwest; CST 102; CST 103; NANT Cancer Vaccine; NK 92 [CD16.158V, ER IL-2]; t-haNK -NantKwest; ZRx 102; ZRx 103; ZRx 104

Latest Information Update: 12 Apr 2018

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At a glance

  • Originator ZelleRx
  • Developer NantKwest
  • Class CAR-NK cell therapies; Gene therapies; Immunotherapies; Natural killer cell therapies
  • Mechanism of Action Cell death stimulants; Immunostimulants; Natural killer cell stimulants; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Preclinical Brain cancer; Breast cancer; Colorectal cancer; Head and neck cancer; Lymphoma; Multiple myeloma; Myelodysplastic syndromes; Non-Hodgkin's lymphoma; Solid tumours; Squamous cell cancer

Most Recent Events

  • 12 Mar 2018 NantKwest plans a clinical trial of CD19.t-haNK for Cancer
  • 12 Mar 2018 NantKwest plans a pahse Ib/II trial of CD19.t-haNK for Cancer (In combination with NANT Cancer Vaccine)
  • 04 Apr 2017 NantKwest and Viracta Therapeutics enter into a collaboration agreement to investigate combination of natural killer cells and VRx 3996 in broad range of cancers
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