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Galactomannan C

Drug Profile

Galactomannan C

Alternative Names: Carbohydrate polymer; DAVANAT®; GM-CT-01

Latest Information Update: 13 Nov 2021

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At a glance

  • Originator Pro-Pharmaceuticals
  • Developer Galectin Therapeutics; Icahn School of Medicine at Mount Sinai; Pro-Pharmaceuticals
  • Class Antineoplastics; Mannans; Polymers
  • Mechanism of Action Galectin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Colorectal cancer

Highest Development Phases

  • Discontinued Biliary cancer; Breast cancer; Colorectal cancer; Hepatic fibrosis; Malignant melanoma

Most Recent Events

  • 22 Mar 2019 Discontinued - Phase-I/II for Malignant melanoma (Combination therapy, Metastatic disease) in Belgium (IV)
  • 12 Mar 2019 Cliniques universitaires Saint-Luc- Université Catholique de Louvain terminates a phase I/II trial in Malignant melanoma (Combination therapy, Metastatic disease) in Belgium (NCT01723813)
  • 10 Aug 2017 Discontinued - Phase-II for Biliary cancer (Combination therapy, Late-stage disease, Metastatic disease, Inoperable/Unresectable) in USA (IV)
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