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Velaglucerase alfa - Takeda

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Drug Profile

Velaglucerase alfa - Takeda

Alternative Names: GA-GCB; GCB; Gene-activated glucocerebrosidase; Glucocerebrosidase - Takeda; Glucosylceramidase - Takeda; Vpriv

Latest Information Update: 29 Jan 2026

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At a glance

  • Originator Shire Pharmaceuticals Group
  • Developer Shire; Takeda
  • Class Glucosidases; Recombinant proteins
  • Mechanism of Action Glucosylceramidase replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Gaucher's disease type I
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Gaucher's disease type I
  • No development reported Gaucher's disease type III

Most Recent Events

  • 29 Jan 2026 Velaglucerase alfa is still in phase III trial for Gaucher's disease type I (In Children, In adolescents, In adults, In elderly) in China
  • 05 Aug 2024 Takeda completes a phase III trial in Gaucher's disease type I (In children, In adolescents, In adults) in China (IV, Infusion) (NCT05529992)
  • 03 Jan 2023 Phase-III clinical trials in Gaucher's disease type I (In children, In adults, In adolescents, In the elderly) in China (IV) (NCT05529992; EudraCT2022-002323-35)

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