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Drug Profile


Alternative Names: GlycoPEG-GCSF; GlycoPEGylated G-CSF; GlycoPEGylated granulocyte colony-stimulating factor; Long-acting G-CSF - BioGeneriX/Teva; Long-acting Granulocyte Colony Stimulating Factor - BioGeneriX/Teva; Lonquex; XM-22

Latest Information Update: 19 Dec 2018

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At a glance

  • Originator BioGeneriX; Neose Technologies
  • Developer BioGeneriX; Teva Pharmaceutical Industries
  • Class Chemoprotectants; Granulocyte colony-stimulating factors; Recombinant proteins
  • Mechanism of Action Granulocyte stimulants; Haematopoiesis stimulants; Neutrophil stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Neutropenia

Most Recent Events

  • 19 Oct 2018 Efficacy and adverse events data from the phase III AVOID trial in Neutropenia presented at the 43rd European Society for Medical Oncology Congress (ESMO-2018)
  • 24 Apr 2018 Merckle GmbH completes the AVOID phase III trial in Neutropenia (In the elderly, Chemotherapy-induced) in Italy (SC) (EudraCT2013-001284-23) (NCT02044276)
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Neutropenia(In adolescents, In children, Chemotherapy-induced) in Bulgaria (SC, Injection)
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