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Samalizumab - Alexion AstraZeneca Rare Disease

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Drug Profile

Samalizumab - Alexion AstraZeneca Rare Disease

Alternative Names: ALXN 6000; anti-CD200 monoclonal antibody-Alexion

Latest Information Update: 27 Jul 2023

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At a glance

  • Originator Alexion Pharmaceuticals
  • Developer Alexion Pharmaceuticals; The Leukemia & Lymphoma Society
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD200 antigen inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Discontinued Acute myeloid leukaemia; Chronic lymphocytic leukaemia; Multiple myeloma; Solid tumours

Most Recent Events

  • 08 Jun 2023 Efficacy and adverse events data from a phase Ib/II Beat AML trial in Acute myeloid leukemia presented at the 28th Congress of the European Haematology Association (EHA-2023)
  • 21 Jul 2021 Alexion Pharmaceuticals has been acquired by AstraZeneca and changed its name to Alexion AstraZeneca Rare Disease
  • 01 Sep 2017 Alexion Pharmaceuticals terminates phase I trial in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT02987504)

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