Samalizumab - Alexion AstraZeneca Rare Disease
Alternative Names: ALXN 6000; anti-CD200 monoclonal antibody-AlexionLatest Information Update: 27 Jul 2023
At a glance
- Originator Alexion Pharmaceuticals
- Developer Alexion Pharmaceuticals; The Leukemia & Lymphoma Society
- Class Antineoplastics; Immunotherapies; Monoclonal antibodies
- Mechanism of Action Antibody-dependent cell cytotoxicity; CD200 antigen inhibitors; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- Discontinued Acute myeloid leukaemia; Chronic lymphocytic leukaemia; Multiple myeloma; Solid tumours
Most Recent Events
- 08 Jun 2023 Efficacy and adverse events data from a phase Ib/II Beat AML trial in Acute myeloid leukemia presented at the 28th Congress of the European Haematology Association (EHA-2023)
- 21 Jul 2021 Alexion Pharmaceuticals has been acquired by AstraZeneca and changed its name to Alexion AstraZeneca Rare Disease
- 01 Sep 2017 Alexion Pharmaceuticals terminates phase I trial in Solid tumours (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT02987504)